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Seven-Year Follow-up of Neurologic Involvement in Behcet Syndrome
Arch Neurol 53:691-694, Akman-Demir,G.,et al, 1996
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Article Abstract
Of the 27 patients who had had headaches without any neurological symptoms or signs previously,2 had developed an acute neurologic attack.In addition,7 patients in this group showed minor abnormalities on neurologic examination and/or other laboratory investigations,without history of any attacks.Among the previous neuro-Behcet group(n=15),as defined by the presence of neurologic signs or symptoms,other than headache,7 had a stationary course,while 8 had been progressive.Three of the latter group had died.Patients with progressive course had had abnormal cerebrospinal fluid findings at the time of the previous report,whereas patients with a stationary course had not.Silent neurologic involvement may occur in Behcet syndrome.Patients should undergo periodic neurologic evaluation.The long-term prognosis in neuro-Behcet syndrome does not seem to be as favorable as we observed in short term followup.Cerebrospinal fluid findings may predict prognosis.
 
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Behcet's syndrome
cerebrospinal fluid
cerebrospinal fluid,abnormal
dural sinus thrombosis
headache
mortality
neurologic signs
prognosis

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